Recently,
Bowden et al 1999
reported an analysis of data from a larger industry-sponsored clinical trial. In
this paper the efficacy of lamotrigine as an add-on treatment was compared for rapid
cycling and non–rapid cycling bipolars, who are commonly difficult to treat. Unfortunately
from this paper it is difficult to come to any conclusion about this comparison with
confidence. There is a lack of detail about how the instruments were used, which affects
the results; about the number of tests, which will affect significance; and about
the dropout pattern, which affects generality.To read this article in full you will need to make a payment
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References
- The efficacy of Lamotrigine in rapid cycling and non–rapid cycling patients with bipolar disorder.Biol Psychiatry. 1999; 45: 953-958
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© 1999 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.
