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Correspondences| Volume 46, ISSUE 12, P1712, December 15, 1999

Landmark analysis of corpus callosum shape in schizophrenia

      I read with interest the paper by
      • Tibbo P.
      • Nopoulos P.
      • Arndt S.
      • Andreasen N.C.
      Corpus callosum shape and size in male patients with schizophrenia.
      “Corpus Callosum Shape and Size in Male Patients with Schizophrenia,” in which they report no difference in corpus callosum shape between patients and normal controls. The methodology of the study is seriously flawed, rendering any conclusions regarding landmark data invalid.
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      References

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        Landmark methods for forms without landmarks.
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        Corpus callosum shape and size in male patients with schizophrenia.
        Biol Psychiatry. 1998; 44: 405-412