Brief report| Volume 40, ISSUE 12, P1308-1310, December 15, 1996

Zinc deficiency in attention-deficit hyperactivity disorder

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        • Aldegunde M
        • Miquez I
        • Veira J
        Effects of pinealectomy on regional brain serotonin metabolism.
        Int J Neurosci. 1985; 26: 9-13
        • American Psychiatric Association
        3rd ed rev. Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Press, New York1987
        • Arnold LE
        • Votolato NA
        • Kleykamp D
        • Baker GB
        • Bornstein RA
        Does hair zinc predict amphetamine improvement of ADDH?.
        Int J Neurosci. 1990; 50: 103-107
        • Colquhon I
        • Bunday S
        A lack of essential fatty acids as a possible cause of hyperactivity in children.
        Med Hypotheses. 1981; 7: 673-679
        • Golub MS
        • Takeuchi PT
        • Keen CL
        • Gershwin ME
        • Hendrickx AG
        • Lonnerdal B
        Modulation of behavioral performance of prepubertal monkeys by moderate dietary zinc deprivation.
        Am J Clin Nutr. 1994; 60: 238-243
        • Halas ES
        • Sandstead HH
        Some effects of prenatal zinc deficiency on behavior of the adult rat.
        Pediatr Res. 1975; 9: 94-97
        • Hess GW
        • Hesse KAF
        • Catalanotto FA
        Behavioral characteristics of rats experiencing chronic zinc deficiency.
        Physiol Behav. 1979; 22: 211-215
        • Kaplan HI
        • Sadock BJ
        • Grebb JA
        Attention deficit disorders.
        in: Kaplan HI Sadock BJ Grebb JA Synopsis of Psychiatry. 7th ed. Williams and Wilkins, Washington, DC1994: 1063-1068
        • Kasperek K
        • Feinendegen LE
        • Lombeck I
        • Bremer HJ
        Serum zinc concentration during childhood.
        Eur J Pediatr. 1977; 126: 199-202
        • Kruesi MJ
        • Rapoport JL
        • Hamburger S
        • et al.
        Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents.
        Arch Gen Psychiatry. 1990; 47: 419-426
        • McGee R
        • Williams S
        • Anderson J
        • McKenzie-Parnell JM
        • Silva PA
        Hyperactivity and serum hair zinc levels in 11-year-old children from the general population.
        Biol Psychiatry. 1990; 28: 165-168
        • Naveh Y
        Zinc deficiency in children.
        Harefuah. 1995; 128: 728-732
        • Orvaschel H
        • Puig-Antich J
        Schedule for affective disorder and schizophrenia for school-age children-epidemiologic Fourth version.
        Nova University, Center for Psychological Study, Baltimore, MD1987
        • Rogers JM
        • Keen CL
        • Hurley LS
        Zinc, copper, and manganese deficiencies in prenatal and neonatal development, with special reference to the central nervous system.
        in: Gabay S Harris J Ho BT Metal Ions in Neurology and Psychiatry. Liss, Ft. Lauderdale, FL1985: 3-34
        • Sandstead HH
        A brief history of the influence of trace elements on brain function.
        Am J Clin Nutr. 1986; 43: 293-298
        • Sandyk R
        Zinc deficiency in attention-deficit hyperactivity disorder.
        Int J Neurosci. 1990; 52 ([letter]): 239-241