Cerebrospinal fluid and plasma gamma-aminobutyric acid in Alzheimer's disease

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        • Adinoff B
        • Kramer G
        • Petty F
        Levels of gammaaminobutyric acid in cerebrospinal fluid and plasma during alcohol withdrawal.
        Psychiatry Res. 1995; 59: 137-144
        • Bareggi SR
        • Franceschi M
        • Bonini L
        • Zecca L
        • Smirne S
        Decreased CSF concentrations of homovanillic acid and γ-amino butyric acid in Alzheimer's disease.
        Arch Neurol. 1982; 39: 709-712
        • Chu D
        • Penney J
        • Young A
        Cortical GABA-B and GABA-A receptors in Alzheimer's disease: A quantitative autoradiographic study.
        Neurology. 1987; 37: 1454-1459
        • Enna SZ
        • Stern LZ
        • Wastek GJ
        • et al.
        Cerebrospinal fluid γ-amino butyric acid variations in neurological disorders.
        Arch Neurol. 1977; 34: 683-685
        • Ferraro TN
        • Hare TA
        Free and conjugated amino acids in human CSF: Influence of age and sex.
        Brain Res. 1985; 338: 53-60
        • Lakke JPWF
        • Teelken AW
        Amino acid abnormalities in cerebrospinal fluid in patients with parkinsonism and extrapyramidal disorders.
        Neurology. 1976; 26: 489-493
        • Löscher W
        GABA in plasma and spinal fluid of different species. Effects of γ-acetylenic GABA, γ-vinyl GABA and sodium valproate.
        J Neurochem. 1979; 32: 1587-1591
        • Manyam BNV
        • Katz L
        • Hare TA
        • et al.
        Levels of γ-amino butyric acid in cerebrospinal fluid in various neurological disorders.
        Arch Neurol. 1980; 37: 352-355
        • Petty F
        • Kramer GL
        • Fulton M
        • et al.
        Low plasma GABA is a trait-like marker for bipolar illness.
        Neuropsychopharmacology. 1993; 9: 125-132
        • Pomara N
        • Deptula D
        • Galloway MP
        • et al.
        CSF GABA in caregiver spouses of Alzheimer patients.
        Am J Psychiatry. 1989; 146: 787-788
        • Rossor MN
        • Garrett NJ
        • Johnson AL
        • et al.
        A postmortem study of the cholinergic and GABA systems in senile dementia.
        Brain. 1982; 105: 313-330
        • Shimohama S
        • Taniguchi T
        • Fujiwara M
        • et al.
        Changes in benzodiazepine receptors in Alzheimer's type dementia.
        Ann Neurol. 1988; 23: 404-406
        • Uhlhaas VS
        • Lanage H
        • Wappenschmidt J
        • et al.
        Free and conjugated CSF and plasma GABA in Huntington's chorea.
        Acta Neurol Scand. 1986; 74: 261-265
        • Zimmer R
        • Teelken AW
        • Trieling WB
        • et al.
        γ-Amino butyric acid and homovanillic acid concentration in the CSF of patients with senile dementia of Alzheimer's type.
        Arch Neurol. 1984; 41: 602-604