Epigenetic mechanisms have been suggested to be located at the interface between the
genetic and the environmental levels. In animal as well as human studies, epigenetic
mechanisms have been proposed to dynamically adjust to environmental challenges such
as stress in an adaptive or maladaptive way [cf. (
1
,
2
)] and thus to contribute to resilience or risk, respectively, toward stress-related
disorders as well as substance abuse disorders, which are inherently tied to stress-related
disorders.
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Article info
Publication history
Accepted:
November 15,
2022
Received:
November 15,
2022
Identification
Copyright
© 2022 Society of Biological Psychiatry.
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- Additive Effects of Stress and Alcohol Exposure on Accelerated Epigenetic Aging in Alcohol Use DisorderBiological PsychiatryVol. 93Issue 4Open Access
