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P651. Emotional Numbing is Associated With Reduced Pain Processing in the Amygdala

      Posttraumatic stress disorder (PTSD) is often associated with altered pain perception such as higher pain threshold. While pain consists of both physiological and emotional components, the latter is often overlooked. A hallmark feature of PTSD is emotional numbing (EN): restricted capacity to experience positive/negative emotions. As both EN and emotional processing of pain converge in the amygdala, here we examine whether individuals diagnosed with PTSD show lower activation to pain in the amygdala compared with combat controls, and whether amygdala response is correlated with EN, using data from two different studies.
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