P462. Genome-Wide Association Study Identifies 15 Common Risk Variants Associated With Obsessive-Compulsive Disorder

      To date, four genome-wide association studies (GWAS) of obsessive-compulsive disorder (OCD) have been published, reporting a high heritability (SNP-heritability=0.28) but finding only one significant single-nucleotide polymorphism (SNP). A substantial increase in sample size will likely lead to further identification of genes and biological pathways mediating susceptibility to OCD.
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