Reward-Related Neural Activity Associated With General Psychopathology in 9- And 10-Year-Olds From the ABCD Study

      The general psychopathology factor (P) accounts for variance common to all mental disorders through a dimensional, multi-domain approach. Relatedly, reward-processing abnormalities have been identified as a transdiagnostic feature across multiple psychopathologies. The present study examined reward-related brain function as a predictor of P over and above relevant demographic and self-report measures. Investigating multi-domain predictors of P may help identify early risk indicators in preadolescence when psychopathology begins to emerge.
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