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Early Career Investigator Commentary| Volume 90, ISSUE 6, e31-e32, September 15, 2021

Critical Developmental Windows of Voltage-Gated Cation Channel Expression in Psychiatric Disorders

  • Noura Al-Juffali
    Correspondence
    Address correspondence to Noura Al-Juffali, B.Sc., M.B.B.S., Ph.D., M.R.C.Psych.
    Affiliations
    Department of Psychiatry, University of Oxford, Oxford, United Kingdom
    Oxford Health NHS Foundation Trust, Oxford, United Kingdom
    Search for articles by this author
      The molecular underpinnings of psychiatric disorders remain elusive despite there being a paramount need to establish druggable targets for their treatment. Genome-wide association studies (GWASs) have identified numerous candidate genes implicated in the pathology of psychiatric disorders. However, a key challenge is to identify time intervals when implicated biological pathways are germane. This information is critical from a drug development perspective because it guides when psychopharmacotherapy should be applied to achieve maximum effect.
      SEE CORRESPONDING ARTICLE ON PAGE 399
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