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Article Info
Publication History
Accepted:
March 30,
2021
Received in revised form:
March 29,
2021
Received:
March 26,
2021
Identification
Copyright
© 2021 Society of Biological Psychiatry.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Nucleus Accumbens Medium Spiny Neuron Subtypes Differentially Regulate Stress-Associated Alterations in Sleep ArchitectureBiological PsychiatryVol. 89Issue 12
- PreviewStress is implicated in the pathophysiology of major depression and posttraumatic stress disorder. These conditions share core features, including motivational deficits, heighted anxiety, and sleep dysregulation. Chronic stress produces these same features in rodents, with some individuals being susceptible or resilient, as seen in humans. While stress-induced neuroadaptations within the nucleus accumbens are implicated in susceptibility-related dysregulation of motivational and emotional behaviors, their effects on sleep are unclear.
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