Breathing in rodents normally overlaps with delta and theta oscillations involved
in oscillatory coupling between prefrontal cortex (PFC) and hippocampus (HC). Recent
studies reported that the respiratory rhythm (RR), mediated by the olfactory bulb
(OB) through monitoring nasal air movement, may promote synchronous brain oscillations
globally, including higher-order brain networks, such as PFC and HC. On the other
hand, Ketamine, known to elicit schizophrenia-like symptoms, strongly disturb EEG
oscillations which was proposed to contribute to cognitive deficits in both schizophrenia
and after Ketamine administration.
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