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Article info
Publication history
Accepted:
December 21,
2020
Received:
December 21,
2020
Identification
Copyright
© 2020 Published by Elsevier Inc on behalf of Society of Biological Psychiatry.
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Access this article on ScienceDirectLinked Article
- Elevated Polygenic Burden for Autism Spectrum Disorder Is Associated With the Broad Autism Phenotype in Mothers of Individuals With Autism Spectrum DisorderBiological PsychiatryVol. 89Issue 5
- PreviewAutism spectrum disorder (ASD) is a multifactorial neurodevelopmental disorder that encompasses a complex and heterogeneous set of traits. Subclinical traits that mirror the core features of ASD, referred to as the broad autism phenotype (BAP), have been documented repeatedly in unaffected relatives and are believed to reflect underlying genetic liability to ASD. The BAP may help inform the etiology of ASD by allowing the stratification of families into more phenotypically and etiologically homogeneous subgroups.
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