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References
- Gene hunting in autism spectrum disorder: On the path to precision medicine.Lancet Neurol. 2015; 14: 1109-1120
- Autism spectrum disorder: Insights into convergent mechanisms from transcriptomics.Nat Rev Genet. 2019; 20: 51-63
- The neuroanatomy of autism – a developmental perspective.J Anat. 2017; 230: 4-15
- FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders.Cell. 2015; 162: 375-390
- Altered proliferation and networks in neural cells derived from idiopathic autistic individuals.Mol Psychiatry. 2017; 22: 820-835
- Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons.Nat Neurosci. 2019; 22: 243-255
- Transcriptome of iPSC-derived neuronal cells reveals a module of co-expressed genes consistently associated with autism spectrum disorder [published online ahead of print Feb 14].Mol Psychiatry. 2020;
- Convergent pathways in idiopathic autism revealed by time course transcriptomic analysis of patient-derived neurons.Sci Rep. 2018; 8: 8423
- A perturbed gene network containing PI3K–AKT, RAS–ERK and WNT–β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity.Nat Neurosci. 2019; 22: 1624-1634
- Atypical neurogenesis in induced pluripotent stem cells from autistic individuals.Biol Psychiatry. 2021; 89: 486-496
Article info
Publication history
Accepted:
December 18,
2020
Received:
December 18,
2020
Identification
Copyright
© 2020 Society of Biological Psychiatry.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Atypical Neurogenesis in Induced Pluripotent Stem Cells From Autistic IndividualsBiological PsychiatryVol. 89Issue 5
- PreviewAutism is a heterogeneous collection of disorders with a complex molecular underpinning. Evidence from postmortem brain studies have indicated that early prenatal development may be altered in autism. Induced pluripotent stem cells (iPSCs) generated from individuals with autism with macrocephaly also indicate prenatal development as a critical period for this condition. But little is known about early altered cellular events during prenatal stages in autism.
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