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Correspondence| Volume 89, ISSUE 6, e35-e36, March 15, 2021

Esketamine for Postpartum Suicidality

      We report the first case of rapid life-saving improvement in postpartum depression (PPD) with severe suicidal ideation/attempt following the introduction of esketamine injections after failing to achieve a response with antidepressants.
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      References

        • Mangla K.
        • Hoffman M.C.
        • Trumpff C.
        • O'Grady S.
        • Monk C.
        Maternal self-harm deaths: an unrecognized and preventable outcome.
        Am J Obstet Gynecol. 2019; 221: 295-303
        • Gressier F.
        • Guillard V.
        • Cazas O.
        • Falissard B.
        • Glangeaud-Freudenthal N.M.
        • Sutter-Dallay A.L.
        Risk factors for suicide attempt in pregnancy and the post-partum period in women with serious mental illnesses.
        J Psychiatr Res. 2017; 84: 284-291
        • Barnes D.L.
        • Brown J.
        Postpartum depression and suicide. Forensic Scholars Today. 4.
        (Available at:)
        • Halbreicht U.
        • Karkun S.
        Cross-cultural and social diversity of prevalence of postpartum depression and depressive symptoms.
        J Affect Disord. 2006; 91: 97-111
        • Friedman S.H.
        • Sorrentino R.
        Commentary: Postpartum psychosis, infanticide, and insanity--implications for forensic psychiatry.
        J Am Acacd Psychiatry Law. 2012; 40: 326-332
        • Kanes S.
        • Colquhoun H.
        • Gunduz-Bruce H.
        • Raines S.
        • Arnold R.
        • Schacterle A.
        • et al.
        Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial.
        Lancet. 2017; 390: 480-489
        • Dadiomov D.
        • Lee K.
        The effects of ketamine on suicidality across various formulations and study settings.
        Ment Health Clin. 2019; 9: 48-60
        • Wilkinson S.T.
        • Ballard E.D.
        • Bloch M.H.
        • Mathew S.J.
        • Murrough J.W.
        • Feder A.
        • et al.
        The effect of a single dose of intravenous ketamine on suicidal ideation: A systematic review and individual participant data meta-analysis.
        Am J Psychiatry. 2018; 175: 150-158
        • Lacerda A.L.T.
        Esketamine/ketamine for treatment-resistant depression.
        Braz J Psychiatry. 2020; 42: 579-580
        • da Frota Ribeiro C.M.
        • Sanacora G.
        • Hoffman R.
        • Ostroff R.
        The use of ketamine for the treatment of depression in the context of psychotic symptoms: To the editor.
        Biol Psychiatry. 2016; 79: e65-e66
        • Ajub E.
        • Lacerda A.L.T.
        Efficacy of esketamine in the treatment of depression with psychotic features: A case series.
        Biol Psychiatry. 2018; 83: e15-e16
        • Powell J.G.
        • Garland S.
        • Preston K.
        • Piszczatoski C.
        Brexanolone (Zulresso): Finally, an FDA-approved treatment for postpartum depression.
        Ann Pharmacother. 2020; 54: 157-163