SEE CORRESPONDING ARTICLE ON PAGE 678 Diagnosis, the process of classification of disorders, has been fundamental to clinical
practice and research in psychiatry. Psychiatric neuroscience has relied on diagnostic
classification systems to understand the biological mechanisms underlying specific
disorders and to better support disease prevention and treatment (
1
). However, as the number and sample sizes of neuroimaging studies have grown, meta-analyses
of neuroimaging data have begun to reveal two points in psychiatric neuroscience:
1) there is notable overlap in the identified abnormalities between individuals with
psychiatric disorders and typically developing control subjects, and 2) identifying
shared versus disorder-specific neurobiological features of psychiatric illness is
critical for supporting preventive and therapeutic efforts in psychiatry. Specifically,
understanding shared versus disorder-specific regional dysfunction may advance the
understanding of pathophysiologic processes underlying specific disorders as well
as processes underlying constructs that are common to several different conventionally
defined psychiatric disorders, facilitate the discovery of neural markers for illness
trajectory, and enhance the development of therapeutics.To read this article in full you will need to make a payment
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Article info
Publication history
Accepted:
July 27,
2020
Received:
July 23,
2020
Identification
Copyright
© 2020 Society of Biological Psychiatry.
