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Article info
Publication history
Accepted:
April 7,
2020
Received:
April 7,
2020
Identification
Copyright
© 2020 Society of Biological Psychiatry.
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- Prefrontal Regulation of Punished Ethanol Self-administrationBiological PsychiatryVol. 87Issue 11
- PreviewA clinical hallmark of alcohol use disorder is persistent drinking despite potential adverse consequences. The ventromedial prefrontal cortex (vmPFC) and dorsomedial prefrontal cortex (dmPFC) are positioned to exert top-down control over subcortical regions, such as the nucleus accumbens shell (NAcS) and basolateral amygdala, which encode positive and negative valence of ethanol (EtOH)-related stimuli. Prior rodent studies have implicated these regions in regulation of punished EtOH self-administration (EtOH-SA).
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