Deep brain stimulation (DBS) of the subcallosal cingulate has been tested in a series
of studies with repeated evidence of sustained long-term effects but with a variable
time course of symptom improvement across cohorts. Several randomized controlled trials
of different DBS brain targets did not show differences between active and sham stimulation,
and a possible cause of failure may have been the prolonged time until clinical response
was seen (
1
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2
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3
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References
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Article info
Publication history
Published online: May 14, 2020
Accepted:
March 20,
2020
Received:
March 17,
2020
Identification
Copyright
© 2020 Society of Biological Psychiatry.
