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Propranolol Decreases Fear Expression by Altering Dentate Gyrus Memory Trace Reactivation

      Post-traumatic stress disorder (PTSD) can develop following a traumatic event and results in heightened fear and anxiety. Although approximately 8% of the US population suffers from PTSD, only two drugs have been approved by the FDA to treat it, both with limited efficacy. Propranolol, a non-selective β-adrenergic antagonist, has shown efficacy in decreasing exaggerated fear, and there has been renewed interest in using it to treat fear disorders.
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