Abstract| Volume 87, ISSUE 9, SUPPLEMENT , S325, May 01, 2020

Probiotic-Induced Changes in Gut Microbial Composition Relate to its Buffering Effect Against the Negative Consequences of Stress on Cognitive Performance

      Probiotics affect emotional processing (including emotional memory and decision making), as well as reduce sensitivity for sad mood in humans. The mechanisms by which probiotics influence behavior and neurobiological measures may include the gut microbiota. However, evidence for the involvement of the gut microbiome in the effect of probiotics on stress-related cognitive performance is lacking in humans. Here, we asked whether the relative abundance of the gut microbiome is altered by probiotics and whether these changes are associated with behavioral and neurobiological variation.
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