Abstract| Volume 87, ISSUE 9, SUPPLEMENT , S251, May 01, 2020

Ambulatory Estimation of Circadian Rhythms Shows Core Body Temperature Phase Precedes Slow Wave Sleep Phase in the Normal Elderly

      Evidence suggests that age-related reductions in slow wave sleep (SWS) are associated with increased risk for Alzheimer’s disease (AD), making it important to understand how SWS is regulated. Evidence also indicates a strong interdependence between SWS onset and a decline in core body temperature (CBT), but causal mechanisms are not understood. We aimed to determine the temporal relationship between CBT and slow-wave activity (SWA) in the normal elderly.
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