Cognitive impairments are considered the core deficits in psychosis, and studies have
revealed similar impairments in youth at clinical high-risk for psychosis (CHR). Dysfunction
in the dorsolateral prefrontal cortex (DLPFC) is the consistently replicated region
underlying such cognitive impairments across phases of psychotic illness. However,
DLPFC-involved connectivity underlying cognitive impairments in the first episode
psychosis (FEP) and CHR remains elusive.
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© 2020 Published by Elsevier Inc.
