Abstract| Volume 87, ISSUE 9, SUPPLEMENT , S158-S159, May 01, 2020

Default Mode Network Remodels Frontoparietal Network in Self-Referential Task

      Default mode network (DMN) is a large-scale brain system originally characterized by neural deactivation during goal-directed tasks and relative activations in “task-negative,” or resting states. Recent works challenge this antagonistic framing, showing that internally directed cognitive tasks can produce greater DMN activation than at rest. This DMN activity is associated with task-linked coupling between DMN and the frontoparietal control network (FPCN), a brain system implicated in guiding goal-oriented cognition. Additional work suggests FPCN has subsystems specializing in externally vs. internally directed tasks, the latter being relatively under-studied. We added to this effort to map internally directed cognition through network analysis of an exemplar internally directed task.
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