Identifying brain biomarkers of disease risk is a growing priority in clinical neuroscience.
The ability to identify meaningful biomarkers is limited by measurement reliability;
unreliable measures are unsuitable for predicting clinical outcomes. Measuring brain
activity using task-fMRI is a major focus of biomarker development; however, the reliability
of task-fMRI has not been systematically evaluated. We present converging evidence
demonstrating poor reliability of task-fMRI measures.
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© 2020 Published by Elsevier Inc.
