SYMPOSIUM| Volume 87, ISSUE 9, SUPPLEMENT , S51-S52, May 01, 2020

Refined PTSD Phenotyping Identifies Additional GWAS Risk Variants and Broader Domains Underlying Risk to Psychopathology

      PTSD is highly correlated with other psychiatric disorders such as major depressive disorder, which can be captured by a higher-level genetic structure. Identification of PTSD-specific risk loci is important for understanding its etiology and improving risk prediction. Thus, incorporation of symptom-level phenotypic information and trauma exposure measures into genetic association studies of PTSD is crucial for advancing analyses and increase overall power.
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