PTSD is highly correlated with other psychiatric disorders such as major depressive
disorder, which can be captured by a higher-level genetic structure. Identification
of PTSD-specific risk loci is important for understanding its etiology and improving
risk prediction. Thus, incorporation of symptom-level phenotypic information and trauma
exposure measures into genetic association studies of PTSD is crucial for advancing
analyses and increase overall power.
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© 2020 Published by Elsevier Inc.
