Perception is an inference process, in which the brain combines low-level sensory
inputs and high-level prior expectations to reconstruct a plausible image of the world.
Influential theories in computational psychiatry suggest that various psychiatric
disorders, including schizophrenia, could be the outcome of such impaired predictive
processing. Among those theories, the Circular Inference framework suggests that an
unconstrained propagation of information in the cortical hierarchy, underlain by an
excitatory to inhibitory imbalance, can generate false percepts and beliefs, similar
to those exhibited by schizophrenia patients.
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© 2020 Published by Elsevier Inc.