Abstract| Volume 87, ISSUE 9, SUPPLEMENT , S41-S42, May 01, 2020

Circular Inference and Hallucinations

      Perception is an inference process, in which the brain combines low-level sensory inputs and high-level prior expectations to reconstruct a plausible image of the world. Influential theories in computational psychiatry suggest that various psychiatric disorders, including schizophrenia, could be the outcome of such impaired predictive processing. Among those theories, the Circular Inference framework suggests that an unconstrained propagation of information in the cortical hierarchy, underlain by an excitatory to inhibitory imbalance, can generate false percepts and beliefs, similar to those exhibited by schizophrenia patients.
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