Shared Normalisation of Sustained Attention-Related Brain Dysfunctions of Stimulants and Non-Stimulant Medications in ADHD

      Non-stimulant medications like atomoxetine (ATX) have shown similar, albeit somewhat lower, efficacy and tolerability to stimulants, such as methylphenidate (MPH), in patients with ADHD. However, their mechanisms of action are not yet well understood. Critically, both drugs have shown similar beneficial effects on attention symptoms in patients with ADHD. Despite this, the neurobiological underpinnings of their effect on attention functions has not been studied previously.
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