Ketamine is an NMDA receptor antagonist and glutamate modulator with rapid antidepressant
effects in patients with treatment resistant depression (TRD). To gain insights into
the etiopathology of TRD and ketamine’s mechanism of action, we examined gene expression
profiles in patients compared to healthy controls (HC) and in patients before and
after ketamine treatment.
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© 2020 Published by Elsevier Inc.