Personalized Neuro-Behavioral Mapping Along the Psychosis and Mood Spectra Emerges From a Low-Dimensional Symptom Geometry

      Mental illness is still diagnosed at the syndrome-level, which imposes limits for quantifying symptom-relevant - and therefore neural - individual variation. Continued failed attempts to rationally develop therapies for specific patients underscores a neuro-behavioral mapping knowledge gap in psychiatry, particularly apparent along the ‘psychosis' spectrum disorders (PSD).
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