Psychotic disorders are linked to cognitive deficits. Foremost among these is impaired
information processing speed. Neuroimaging in healthy participants links processing
speed to fronto-parietal control network (FPCN) activity. Notably, this finding implicates
both the cortical and cerebellar nodes of the FPCN. Cerebellar-cortical hypoconnectivity
is a well replicated neuroimaging phenotype in psychotic disorders. We hypothesized
that cerebellar-cortical hypoconnectivity is a direct cause of impaired information
processing speed. We tested this hypothesis in a two-part experiment.
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© 2020 Published by Elsevier Inc.
