Progressive changes in neurobiology and cognition have been reported following psychosis
onset; however, findings have been inconsistent, perhaps due in part to heterogeneity
in cognitive, neurobiological, and clinical presentations commonly observed in psychosis.
Abnormalities in brain structure and connectivity are associated with distinct cognitive
subtypes cross-sectionally. Here we leverage this heterogeneity to characterize neuroprogressive
trajectories over the first year of illness in patients with psychosis.
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© 2020 Published by Elsevier Inc.
