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Article info
Publication history
Accepted:
January 7,
2020
Received in revised form:
January 3,
2020
Received:
December 8,
2019
Identification
Copyright
© 2020 Society of Biological Psychiatry.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Recent Efforts to Dissect the Genetic Basis of Alcohol Use and AbuseBiological PsychiatryVol. 87Issue 7
- PreviewAlcohol use disorder (AUD) is defined by several symptom criteria, which can be dissected further at the genetic level. Over the past several years, our understanding of the genetic factors influencing alcohol use and abuse has progressed tremendously; numerous loci have been implicated in different aspects of alcohol use. Previously known associations with alcohol-metabolizing enzymes (ADH1B, ALDH2) have been replicated definitively. In addition, novel associations with loci containing the genes KLB, GCKR, CRHR1, and CADM2 have been reported.
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