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Article info
Publication history
Accepted:
November 8,
2019
Received:
November 7,
2019
Identification
Copyright
© 2019 Published by Elsevier Inc. All rights reserved.
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- Maternal Prenatal Stress Is Associated With Altered Uncinate Fasciculus Microstructure in Premature NeonatesBiological PsychiatryVol. 87Issue 6
- PreviewMaternal prenatal stress exposure (PNSE) increases risk for adverse psychiatric and behavioral outcomes in offspring. The biological basis for this elevated risk is poorly understood but may involve alterations to the neurodevelopmental trajectory of white matter tracts within the limbic system, particularly the uncinate fasciculus. Additionally, preterm birth is associated with both impaired white matter development and adverse developmental outcomes. In this study we hypothesized that higher maternal PNSE was associated with altered uncinate fasciculus microstructure in offspring.
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