Commentary| Volume 86, ISSUE 12, P879-880, December 15, 2019

Keep the Change: Embracing Variability as a Path to Richer Theoretical Models of Borderline Personality Disorder

  • Sarah K. Fineberg
    Address correspondence to Sarah K. Fineberg, M.D., Ph.D., Connecticut Mental Health Center, Room 528, 34 Park Street, New Haven, CT 06519.
    Department of Psychiatry, Yale University, and the Connecticut Mental Health Center, New Haven, Connecticut
    Search for articles by this author
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Biological Psychiatry
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Lenzenweger M.F.
        • Lane M.C.
        • Loranger A.W.
        • Kessler R.C.
        DSM-IV personality disorders in the National Comorbidity Survey Replication.
        Biol Psychiatry. 2007; 62: 553-564
        • Gunderson J.G.
        • Herpertz S.C.
        • Skodol A.E.
        • Torgersen S.
        • Zanarini M.C.
        Borderline personality disorder.
        Nat Rev Dis Primers. 2018; 4: 18029
        • Zanarini M.C.
        • Frankenburg F.R.
        • Reich D.B.
        • Fitzmaurice G.
        Attainment and stability of sustained symptomatic remission and recovery among patients with borderline personality disorder and axis II comparison subjects: A 16-year prospective follow-up study.
        Am J Psychiatry. 2012; 169: 476-483
        • Bilek E.
        • Itz M.L.
        • Stößel G.
        • Ma R.
        • Berhe O.
        • Clement L.
        • et al.
        Deficient amygdala habituation to threatening stimuli in borderline personality disorder relates to adverse childhood experiences.
        Biol Psychiatry. 2019; 86: 930-938
        • Schulze L.
        • Schmahl C.
        • Niedtfeld I.
        Neural correlates of disturbed emotion processing in borderline personality disorder: A multimodal meta-analysis.
        Biol Psychiatry. 2016; 79: 97-106
        • Zimmerman M.
        • Multach M.D.
        • Dalrymple K.
        • Chelminski I.
        Clinically useful screen for borderline personality disorder in psychiatric out-patients.
        Br J Psychiatry. 2017; 210: 165-166
        • Fineberg S.K.
        • Leavitt J.
        • Stahl D.S.
        • Kronemer S.
        • Landry C.D.
        • Alexander-Bloch A.
        • et al.
        Differential valuation and learning from social and nonsocial cues in borderline personality disorder.
        Biol Psychiatry. 2018; 84: 838-845
        • Hula A.
        • Vilares I.
        • Lohrenz T.
        • Dayan P.
        • Montague P.R.
        A model of risk and mental state shifts during social interaction.
        PLoS Comput Biol. 2018; 14e1005935
        • Zaehringer J.
        • Ende G.
        • Santangelo P.S.
        • Kleindienst N.
        • Ruf M.
        • Bertsch K.
        • et al.
        Improved emotion regulation after neurofeedback. A single arm trial in patients with borderline personality disorder [published online ahead of print Jun 26].
        PsyArXiv. 2019;
        • Denny B.T.
        • Fan J.
        • Fels S.
        • Galitzer H.
        • Schiller D.
        • Koenigsberg H.W.
        Sensitization of the neural salience network to repeated emotional stimuli following initial habituation in patients with borderline personality disorder.
        Am J Psychiatry. 2018; 175: 657-664

      Linked Article