Assessing the Candidates

  • Anil K. Malhotra
    Address correspondence to Anil K. Malhotra, M.D., The Zucker Hillside Hospital, 75-59 263rd Street, Glen Oaks, NY 11004.
    The Zucker Hillside Hospital, The Feinstein Institutes for Medical Research, Zucker School of Medicine at Hofstra/Northwell, Glen Oaks, New York
    Search for articles by this author
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Biological Psychiatry
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Sullivan P.F.
        • Neale M.C.
        • Silverman M.A.
        • Harris-Kerr C.
        • Myakishev M.V.
        • Wormley B.
        • et al.
        An association study of DRD5 with smoking initiation and progression to nicotine dependence.
        Am J Med Genet. 2001; 105: 259-265
        • Egan M.F.
        • Goldberg T.E.
        • Kolachana R.S.
        • Callicott J.H.
        • Mazzanti C.M.
        • Straub R.E.
        • et al.
        Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia.
        Proc Natl Acad Sci U S A. 2001; 98: 6917-6922
        • Lencz T.
        • Robinson D.G.
        • Xu K.
        • Ekholm J.
        • Sevy S.
        • Gunduz-Bruce H.
        • et al.
        DRD2 promoter region variation predicts sustained response to antipsychotic medication in first episode schizophrenia.
        Am J Psych. 2006; 163: 529-531
        • Arinami T.
        • Gao M.
        • Hamaguchi H.
        • Toru M.
        A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia.
        Hum Mol Genet. 1997; 6: 577-582
        • Lencz T.
        • Morgan T.V.
        • Athanasiou M.
        • Dain B.
        • Reed C.R.
        • Kane J.M.
        • et al.
        Converging evidence for a psuedoautosomal cytokine receptor gene locus in schizophrenia.
        Mol Psychiatry. 2007; 12: 572-580
        • Schizophrenia Working Group of the Psychiatric Genomics Consortium
        Biological insights from 108 schizophrenia-associated genetic loci.
        Nature. 2014; 51: 421-427
        • Demontis D.
        • Walters R.K.
        • Martin J.
        • Mattheisen M.
        • Als T.D.
        • Agerbo E.
        • et al.
        Discovery of the first genome-wide significant risk loci for attention-deficit/hyperactivity disorder.
        Nat Genet. 2019; 51: 63-75
        • Duncan L.E.
        • Ostacher M.
        • Ballon J.
        How genome-wide association studies (GWAS) made traditional candidate gene studies obsolete.
        Neuropsychopharmacology. 2019; 44: 1518-1523
        • Miguel P.M.
        • Pereira L.O.
        • Barth B.
        • de Mendonça Filho E.J.
        • Pokhvisneva I.
        • Nguyen T.T.T.
        • et al.
        Prefrontal cortex dopamine transporter gene network moderates the effect of perinatal hypoxic-ischemic conditions on cognitive flexibility and brain gray matter density in children.
        Biol Psychiatry. 2019; 86: 621-630
        • Tunbridge E.M.
        • Narajos M.
        • Harrison C.H.
        • Beresford C.
        • Cipriani A.
        • Harrison P.J.
        Which dopamine polymorphisms are functional? Systematic review and meta-analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1, and VMAT2.
        Biol Psychiatry. 2019; 86: 608-620

      Linked Article