Neurodegeneration with brain iron accumulation (NBIA) is defined as an accumulation
of iron in the basal ganglia associated with neurologic and psychiatric symptoms (
1
). Its estimated prevalence is 1:1,000,000 (
2
). Cardinal symptoms include dystonia; spasticity and/or Parkinsonian syndrome, often
associated with cognitive decline (
3
,
4
); and psychiatric disorders such as obsessive-compulsive disorder (OCD) (
3
,
5
,
6
), depression (
7
), or psychosis (
8
).To read this article in full you will need to make a payment
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References
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Article Info
Publication History
Published online: August 28, 2019
Accepted:
July 14,
2019
Received in revised form:
June 23,
2019
Identification
Copyright
© 2019 Society of Biological Psychiatry.
