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References
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Article info
Publication history
Accepted:
March 11,
2019
Received:
March 11,
2019
Identification
Copyright
© 2019 Published by Elsevier Inc on behalf of Society of Biological Psychiatry.
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Access this article on ScienceDirectLinked Article
- A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder: Clinical and Imaging Evidence for Dissociable EffectsBiological PsychiatryVol. 85Issue 9
- PreviewDeep brain stimulation (DBS) is an emerging treatment for severe obsessive-compulsive disorder (OCD). We compared the efficacy of ventral capsule/ventral striatal (VC/VS) and anteromedial subthalamic nucleus (amSTN) DBS in the same patients and tested for mechanistic differences on mood and cognitive flexibility and associated neural circuitry. The possible synergistic benefit of DBS at both sites and cognitive behavioral therapy was explored.
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