Deficits in fear extinction are implicated in the pathophysiology of anxiety disorders
such as posttraumatic stress disorder. Recent studies suggest that signaling via the
cannabinoid receptor 1 (CB1R) is essential for fear extinction. A common variant in
the gene encoding the CB1R (CNR1) has been linked to poor extinction learning in adults.
However, anxiety disorders typically begin in childhood. The present study examines
the effect of CNR1 on fear extinction learning and its later recall in children.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Biological PsychiatryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Identification
Copyright
© 2019 Published by Elsevier Inc.
