T137. Psilocybin-Assisted Group Therapy for Demoralization in Long-Term AIDS Survivors

      Long-term AIDS Survivors (LTAS) are people with HIV diagnosed prior to the advent of antiretroviral therapy. LTAS suffer high rates of multiple psychiatric illnesses; demoralization is a syndrome common in LTAS and is characterized by a sense of helplessness, hopelessness, and a loss of meaning and purpose in life. Psilocybin is a 5HT2A agonist and classic psychedelic that can improve depression and anxiety in cancer patients when combined with individual psychotherapy, possibly by decreasing demoralization.
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