The impact of maternal immune activation (MIA) on neurodevelopment has been widely
studied in rodents. However, only two non-human primate (NHP) neuroimaging studies
have been reported. Viral MIA caused reduction of grey and white matter while bacterial
MIA was associated with enlargement of brain structures at 12 months. In a pilot study,
MIA NHP’s showed typical early development with behavioral changes after 2 years.
Here, we investigated brain structural alterations associated with MIA in a new sample
of NHP’s using a longitudinal neuroimaging design.
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© 2019 Published by Elsevier Inc.
