SEE CORRESPONDING ARTICLE ON PAGE 893
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Biological Psychiatry
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Clues on the coding of reward cues by the nucleus accumbens.Proc Natl Acad Sci U S A. 2016; 113: 2560-2562
- Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections.Nat Neurosci. 2015; 18: 1230-1232
- Cocaine-induced structural plasticity in input regions to distinct cell types in nucleus accumbens.Biol Psychiatry. 2018; 84: 893-904
- Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens.Neuron. 2012; 76: 790-803
- Pathway- and cell-specific kappa-opioid receptor modulation of excitation-inhibition balance differentially gates D1 and D2 accumbens neuron activity.Neuron. 2017; 93: 147-163
- The striatal balancing act in drug addiction: Distinct roles of direct and indirect pathway medium spiny neurons.Front Neuroanat. 2011; 5: 41
- Circuitry of self-control and its role in reducing addiction.Trends Cogn Sci. 2015; 19: 439-444
- Cocaine exposure reorganizes cell type- and input-specific connectivity in the nucleus accumbens.Nat Neurosci. 2014; 17: 1198-1207
- Loss of plasticity in the D2-accumbens pallidal pathway promotes cocaine seeking.J Neurosci. 2017; 37: 757-767
- The emergence of a circuit model for addiction.Annu Rev Neurosci. 2016; 39: 257-276
Accepted: October 10, 2018
Received: October 8, 2018
© 2018 Society of Biological Psychiatry.
ScienceDirectAccess this article on ScienceDirect
- Cocaine-Induced Structural Plasticity in Input Regions to Distinct Cell Types in Nucleus AccumbensBiological PsychiatryVol. 84Issue 12
- PreviewThe nucleus accumbens (NAc) is a brain region implicated in pathological motivated behaviors such as drug addiction and is composed predominantly of two discrete populations of neurons, dopamine receptor-1– and dopamine receptor-2–expressing medium spiny neurons (D1-MSNs and D2-MSNs, respectively). It is unclear whether these populations receive inputs from different brain areas and whether input regions to these cell types undergo distinct structural adaptations in response to the administration of addictive drugs such as cocaine.