S253. Sleep Disturbances, Disruption of Circadian Rhythm and Loss of Daily Melatonin Secretion in CAF Military Personnel Suffering From Post-Traumatic Stress Disorder

      According to DSM-5, sleep disturbance is a core feature of PTSD. About 70% of individuals with PTSD have co-occurring sleep problems, reporting greater trouble initiating and maintaining sleep. Melatonin is secreted by the pineal gland during physiologic night, synchronizing circadian timing and regulating sleep–wake cycle. This prospective investigation examined sleep characteristics and nocturnal melatonin production in military PTSD sufferers with endorsed sleep difficulties.
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