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S52. Optogenetic Interrogation of Prefrontal-Amygdala Synaptic Development

      Early life experiences critically define cognitive and mental health function throughout life. Childhood and adolescence are the predominant age of onset for the majority of mental disorders, periods in which key brain areas involved in emotional processing, such as medial prefrontal cortex (mPFC) and amygdala, are maturing. Anatomical and morphological changes occur in both these areas during early life; nevertheless, how these changes affect circuit function and its consequences to the onset of mental illness is currently unknown.
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