Veterans are at increased risk of developing PTSD resulting from a number of factors
including military-related combat. Structural and functional neuroimaging studies
in patients with PTSD have demonstrated alterations in the anterior cingulate cortex
(ACC). Altered Gamma-aminobutyric acid (GABA), the principal inhibitory neurotransmitter
and modulator of neuronal excitability, has been implicated in PTSD. However, studies
of ACC GABA in veterans are scarce. The current study investigated differences in
GABA in veterans with and without PTSD using proton magnetic resonance spectroscopy
(1H-MRS).
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© 2018 Published by Elsevier Inc.