41. Telomere Length, Epigenetic Aging and Depression in the Netherlands Study of Depression and Anxiety (NESDA)

      Patients with depression show increased risk of developing aging-related diseases. General literature shows accelerated aging in depression by shorter telomere length (TL), also found in NESDA (Cohen’s d=0.12). Here, we sought to confirm accelerated biological aging in depression using a novel method based on DNA methylation (DNAm) patterns, and whether these patterns impact disease characteristics.
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