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14. Glutamatergic Signaling and PSD Proteome in Schizophrenia

      The postsynaptic density (PSD) harbors multiple pathways implicated for schizophrenia and is the epicenter of dendritic spines. Critical to PSD pathophysiology are alterations in signaling and PSD proteome and their relationship. We analyzed Src kinase hypoactivity as a molecular signature of GluN hypofunction and its association with PSD proteome dysregulation in schizophrenia.
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