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Eat to Live or Live to Eat? The Neurobiology of Appetite Regulation

      From Dante’s Inferno (
      • Alghieri D.
      • Doré G.
      Dante’s inferno, new ed. [Cary HF, trans.].
      ), composed in the 14th century, to Roald Dahl’s Charlie and the Chocolate Factory (
      • Dahl R.
      Charlie and the Chocolate Factory.
      ), centuries of literature consistently portray obese characters as vile and unrestrained. Even today, the continued stigma associated with obesity may contribute to many biopsychosocial problems, including mental health disorders, substance use, and stress (
      • Papadopoulos S.
      • Brennan L.
      Correlates of weight stigma in adults with overweight and obesity: A systematic literature review.
      ). As worldwide obesity rates rise (
      • Val-Laillet D.
      • Aarts E.
      • Weber B.
      • Ferrari M.
      • Quaresima V.
      • Stoeckel L.E.
      • et al.
      Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity.
      ) we are only now coming to appreciate the neurobiological underpinnings of what has often been construed as willful self-indulgence.
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      References

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        Correlates of weight stigma in adults with overweight and obesity: A systematic literature review.
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        • Ferrari M.
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        Neuroimaging and neuromodulation approaches to study eating behavior and prevent and treat eating disorders and obesity.
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