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915. Epigenetic Mediation of Temporal Changes in Psychiatric Symptoms: A Pilot Study

      Despite the toll psychiatric disorders have on modern-day society, we know relatively little on the mechanisms at the root of their emergence, progression and remission. Evidence indicates that DNA methylation plays a role in schizophrenia and mood disorders, although research relied mostly on cross-sectional designs. This pilot study describes changes in DNA methylation over time in relation to changes in psychotic and depressive symptoms in diseases related genes (e.g., BDNF, COMT1, FKBP5).
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