196. The Neural Correlates of Compulsive Alcohol Seeking

      A hallmark of alcohol addiction is continued alcohol seeking despite adverse consequences. Animal models have identified the medial prefrontal cortex and insula as key regions for compulsive alcohol seeking (Seif et al., 2013). Despite the importance of compulsivity in addiction, there have been few human studies investigating this phenomenon. Here, we translate a preclinical paradigm to investigate the neural substrates of compulsive alcohol seeking in human participants.
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