Distinct regions and cell types in the bed nucleus of the stria terminalis (BNST)
act to modulate anxiety in opposing ways. A history of chronic stress increases anxiety-like
behavior and has lasting electrophysiological effects on the neurons in the BNST.
However, the opposing circuits within the BNST suggest that stress may have differential
effects on the individual cell types that comprise these circuits in order to shift
the balance of the circuit to favor anxiogenesis. Yet the effects of stress are generally
examined by treating all neurons within a particular region of the BNST as a homologous
population
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© 2017 Published by Elsevier Inc.
