Rodent studies demonstrate that the BNST mediates sustained anxiety-like responses
to uncertain threat, in contrast to the amygdala which mediates fear-like responses
to immediate threats. While these data suggest an important role, the BNST has been
remarkably understudied in humans. We recently overcame the technological issues that
limited neuroimaging of the human BNST (Avery, 2014). Here we report on a translational
task designed to directly compare BNST and amygdala function in humans.
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