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105. Human BNST is Selective to Uncertain Threat and Modulated by Anxiety

      Rodent studies demonstrate that the BNST mediates sustained anxiety-like responses to uncertain threat, in contrast to the amygdala which mediates fear-like responses to immediate threats. While these data suggest an important role, the BNST has been remarkably understudied in humans. We recently overcame the technological issues that limited neuroimaging of the human BNST (Avery, 2014). Here we report on a translational task designed to directly compare BNST and amygdala function in humans.
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